Combined Technologies for Microfabricating Elastomeric Cardiac Tissue Engineering Scaffolds
نویسندگان
چکیده
منابع مشابه
Elastomeric PGS Scaffolds in Arterial Tissue Engineering
Cardiovascular disease is one of the leading cause of mortality in the US and especially, coronary artery disease increases with an aging population and increasing obesity. Currently, bypass surgery using autologous vessels, allografts, and synthetic grafts are known as a commonly used for arterial substitutes. However, these grafts have limited applications when an inner diameter of arteries i...
متن کاملNovel Biopolymers/Functionalized Multi-Walled Carbon Nanotube Composite Scaffolds for Cardiac Tissue Engineering
Abstract This work introduces the novel gelatin/chitosan blend scaffolds containing different amounts of functionalized multi-walled carbon nanotubes (f-MWCNTs) up to 0.1wt%, which were prepared by freeze drying (freezing and lyophilization). The composite scaffolds were characterized by Fourier transformed infrared spectroscopy (FTIR) to distinguish the functional groups and different bonds in...
متن کاملAligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering
Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
متن کاملElectrically Conductive Chitosan/Carbon Scaffolds for Cardiac Tissue Engineering
In this work, carbon nanofibers were used as doping material to develop a highly conductive chitosan-based composite. Scaffolds based on chitosan only and chitosan/carbon composites were prepared by precipitation. Carbon nanofibers were homogeneously dispersed throughout the chitosan matrix, and the composite scaffold was highly porous with fully interconnected pores. Chitosan/carbon scaffolds ...
متن کاملProangiogenic scaffolds as functional templates for cardiac tissue engineering.
We demonstrate here a cardiac tissue-engineering strategy addressing multicellular organization, integration into host myocardium, and directional cues to reconstruct the functional architecture of heart muscle. Microtemplating is used to shape poly(2-hydroxyethyl methacrylate-co-methacrylic acid) hydrogel into a tissue-engineering scaffold with architectures driving heart tissue integration. T...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Macromolecular Bioscience
سال: 2010
ISSN: 1616-5187
DOI: 10.1002/mabi.201000165